Trial methodology research partnership wins prestigious international award

一个研究伙伴关系, in which 万博官方app下载 is a core partner, has won a prestigious international award for making trials of new healthcare treatments more efficient and effective.

葆拉·威廉姆森教授, the University of Liverpool lead, and her colleagues won one of the 2021 Cochrane-REWARD prizes for reducing research waste through the work conducted by the Medical 研究 Council (MRC)/National Institute for Health 研究 (NIHR) Trials Methodology 研究 Partnership (TMRP), 网络集线器::TMRP.ac.uk)

Background

The MRC/NIHR funded TMRP brings together the HTMR Network, 英国健康数据研究所, UKCRC注册了CTU网络, 英国试验经理网络, HRB Trials Methodology 研究 Network (Ireland), 全球卫生网络, and 25 UK universities – of which 阿伯丁 is one. This research ensures health research, practice and policy are built on the best evidence; and maximises benefits for 病人 and 公众. 

Randomised trials are the cornerstone of evidence-based healthcare because they offer the best tests of treatments and health care interventions.

研究垃圾

Waste occurs during five stages of research production: question selection, 研究设计, 研究行为, 出版, 和报告. Much of this waste appears to be avoidable or remediable, but there are few proposed solutions.

The evidence base for how to make the trials process more efficient is something the TMRP has contributed significantly to.

TMRP members work together as a community of practice, strengthening links between trialists, 方法研究, 临床医生, 病人, 公众, 和资助者. TMRP includes eight Working Groups: Adaptive Designs; Global Health; Health Economics; Health Informatics; Outcomes; Statistical Analysis; Stratified Medicine; Trial Conduct.

The impact of better networking has led to:         

•             better, more impactful research 
•             ability to pivot to COVID-19 projects 
•             less duplication of effort 
•             value for money 
•             increased education and knowledge exchange  

更有效的COVID试验 

An example of TMRP’s impact can be seen in the improvement of COVID-19 related trials. New trial designs have led to more efficient and expedient trials. By using the same control group for several evaluations, fewer 病人 need to be randomised. The ability to add and remove treatments means that ineffective or highly beneficial treatments are identified quicker and trial infrastructure only has to be set up once. 

凯蒂Gillies博士 (万博官方app下载 lead and Trial Conduct Working Group co-lead), said: “The TMRP network has provided a community of practice that has had the ability to be agile and pivot to address some of the key questions for COVID-19 trials and much more.  We’re delighted to have our work recognised with this award. TMRP strives to improve health by improving research.”

The team picked up the award at the Cochrane Connects meeting on 1 3月ch 2022.

*万博官方app下载 led initiative Trial Forge was the recipient of this 奖在2019年.

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